As it stands I cannot loop regions with early notes. They just don't play at all. So I effectively can't easily arrange regions in the timeline or easily loop things. I just wasn't sure if this bizarre behavior was intentional or not since I only just came from L9 and a lot can change in a decade so I didn't know if I was missing something like a preference or some paramete! Oy! So you are confirming that what I'm experiencing is not intended behavior. Is this problem already on your bug list here? You seem to not have heard of it before.
I have attached zip file of project here. It's one region on one track with one note looped. The note is one tick early and will not play! If I move it a tick later (to the one of the measure), it plays.
MIDI Test.zip